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OROGO PRODUCT CATEGORY

2'-O-MOE Nucleosides

Quick view. 2′-O-methoxyethyl nucleosides and protected intermediates for antisense oligonucleotide chemistry. This category currently includes 29 products. 2'-O-MOE Nucleosides products serve as starting materials, protected intermediates and analytical comparators in nucleoside, nucleotide and oligonucleotide chemistry.

Products29
Use scopeResearch use only
Pack sizeCustomized to requirements
SupportSelection and custom synthesis review

Category guide

Typical use

2'-O-MOE Nucleosides products serve as starting materials, protected intermediates and analytical comparators in nucleoside, nucleotide and oligonucleotide chemistry.

How to select

Confirm anomeric and sugar stereochemistry, base identity, substitution position, protecting-group pattern and required downstream transformation.

How to qualify

Use orthogonal identity data such as NMR and MS together with chromatographic purity, water or residual-solvent review and route-specific impurity controls.

Product-family considerations

Common advantages
  • Nucleoside catalogs provide flexible entry points for protecting-group, phosphorylation and glycosylation-route development.
  • Availability of related analogs helps researchers compare base, sugar and substitution effects systematically.
Common limitations
  • Downstream use often requires additional protection, activation or purification before incorporation into oligonucleotide workflows.
  • Isomeric purity, water content and residual solvents should be matched to the planned chemistry.

Category literature

These publications provide background for the 2'-O-MOE Nucleosides product family. Individual product pages only show additional product- or feature-relevant references.

Selection checklist

Exact identityMatch the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable.
SpecificationDefine target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits.
Workflow fitShare the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility.
Supply needProvide initial quantity, expected future scale, packaging preference, timeline and documentation requirements.

Product comparison

This snapshot compares up to eight products in the current catalog order. It uses published catalog fields only; confirm the exact form, pack size, specification and current availability by inquiry.

Swipe or scroll horizontally to compare all fields.

Product nameOR catalog no.CASPurity / specificationSupply status
2'-O-(2-Methoxyethyl)inosineOR-2OMN-0001545374-76-3By inquiryInquiry only
3'-O-TBDMS-2'-O-MOE-5-methyluridineOR-2MOE-00011221967-92-5By inquiryInquiry only
5'-O-DMTr-2'-O-MOE-N4-acetylcytidineOR-2MOE-00031345716-47-3By inquiryInquiry only
3'-O-(tert-Butyldimethylsilyl)-2'-O-(2-methoxyethyl)uridineOR-2MOE-00041345716-52-0By inquiryInquiry only
5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosineOR-2MOE-00051384253-67-1By inquiryInquiry only
N2-Isobutyryl-2'-O-(2-methoxyethyl)guanosineOR-2MOE-0022440327-50-4By inquiryInquiry only
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyladenosineOR-2MOE-0033251647-48-0By inquiryInquiry only
2'-O-(2-Methoxyethyl)-5-methylcytidineOR-MN-0167244105-55-3By inquiryInquiry only

29 products

Chemical structure of 2'-O-(2-methoxyethyl)inosine2'-O-(2-Methoxyethyl)inosine

By inquiry · CAS: 545374-76-3

OR-2OMN-0001
Chemical structure of 3'-O-TBDMS-2'-O-MOE-5-methyluridine3'-O-TBDMS-2'-O-MOE-5-methyluridine

By inquiry · CAS: 1221967-92-5

OR-2MOE-0001
Chemical structure of 5'-O-DMTr-2'-O-MOE-N4-acetylcytidine5'-O-DMTr-2'-O-MOE-N4-acetylcytidine

By inquiry · CAS: 1345716-47-3

OR-2MOE-0003
Chemical structure of 3'-O-(tert-Butyldimethylsilyl)-2'-O-(2-methoxyethyl)uridine3'-O-(tert-Butyldimethylsilyl)-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: 1345716-52-0

OR-2MOE-0004
Chemical structure of 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine

By inquiry · CAS: 1384253-67-1

OR-2MOE-0005
Chemical structure of N2-Isobutyryl-2'-O-(2-methoxyethyl)guanosineN2-Isobutyryl-2'-O-(2-methoxyethyl)guanosine

By inquiry · CAS: 440327-50-4

OR-2MOE-0022
Chemical structure of N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyladenosineN6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyladenosine

By inquiry · CAS: 251647-48-0

OR-2MOE-0033
Chemical structure of 2'-O-(2-Methoxyethyl)-5-methylcytidine2'-O-(2-Methoxyethyl)-5-methylcytidine

By inquiry · CAS: 244105-55-3

OR-MN-0167
Chemical structure of 2'-O-(2-Methoxyethyl)guanosine2'-O-(2-Methoxyethyl)guanosine

By inquiry · CAS: 473278-54-5

OR-MN-0168
Chemical structure of 2'-O-(2-Methoxyethyl)adenosine2'-O-(2-Methoxyethyl)adenosine

By inquiry · CAS: 168427-74-5

OR-MN-0169
Chemical structure of 2'-O-(2-Methoxyethyl)cytidine2'-O-(2-Methoxyethyl)cytidine

By inquiry · CAS: 223777-16-0

OR-MN-0170
Chemical structure of 2'-O-(2-Methoxyethyl)uridine2'-O-(2-Methoxyethyl)uridine

By inquiry · CAS: 223777-15-9

OR-MN-0171
Chemical structure of 2'-O-(2-Methoxyethyl)-5-methyluridine2'-O-(2-Methoxyethyl)-5-methyluridine

By inquiry · CAS: 163759-49-7

OR-MN-0174
Structure of 2-Amino-2'-O-(2-methoxyethyl)adenosine OR-2MOE-00172-Amino-2'-O-(2-methoxyethyl)adenosine

By inquiry · CAS: 256224-13-2

OR-2MOE-0017
Structure of OR-2MOE-00064',5'-Didehydro-2'-O-(2-methoxyethyl)-5-methyluridine

By inquiry · CAS: 2095417-31-3

OR-2MOE-0006
Structure of OR-2MOE-00075'-Deoxy-5'-iodo-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: 2095417-41-5

OR-2MOE-0007
Structure of OR-2MOE-00085'-Azido-5'-deoxy-2'-O-(2-methoxyethyl)-5-methyluridine

By inquiry · CAS: 2095417-42-6

OR-2MOE-0008
Structure of OR-2MOE-00095-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: 2095417-51-7

OR-2MOE-0009
Structure of OR-2MOE-00105'-Deoxy-5'-iodo-2'-O-(2-methoxyethyl)-5-methyluridine

By inquiry · CAS: 2095417-53-9

OR-2MOE-0010
Structure of OR-2MOE-00115'-Azido-5'-deoxy-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: 2095417-60-8

OR-2MOE-0011
Structure of OR-2MOE-00124',5'-Didehydro-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: 2095417-78-8

OR-2MOE-0012
Structure of 5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine OR-2MOE-00135-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: 2305415-77-2

OR-2MOE-0013
Structure of N3-Methyl-2'-O-(2-methoxyethyl)uridine OR-2MOE-0014N3-Methyl-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: 2305416-12-8

OR-2MOE-0014
Structure of N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)cytidine OR-2MOE-0015N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)cytidine

By inquiry · CAS: 251647-49-1

OR-2MOE-0015
Structure of 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)uridine OR-2MOE-00165'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: 251647-51-5

OR-2MOE-0016
Chemical structure of 3'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine3'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine

By inquiry · CAS: N/A

OR-2MOE-0018
Chemical structure of N1-Methyl-2'-O-(2-methoxyethyl)guanosineN1-Methyl-2'-O-(2-methoxyethyl)guanosine

By inquiry · CAS: N/A

OR-2MOE-0020
Chemical structure of N1-Methyl-2'-O-(2-methoxyethyl)inosineN1-Methyl-2'-O-(2-methoxyethyl)inosine

By inquiry · CAS: N/A

OR-2MOE-0021
Chemical structure of N3,5-Dimethyl-2'-O-(2-methoxyethyl)uridineN3,5-Dimethyl-2'-O-(2-methoxyethyl)uridine

By inquiry · CAS: N/A

OR-2MOE-0025

Frequently asked questions

What are typical uses for 2'-O-MOE Nucleosides?

2'-O-MOE Nucleosides products serve as starting materials, protected intermediates and analytical comparators in nucleoside, nucleotide and oligonucleotide chemistry.

What should be confirmed before ordering 2'-O-MOE Nucleosides?

Confirm anomeric and sugar stereochemistry, base identity, substitution position, protecting-group pattern and required downstream transformation.

Are custom quantities or related analogs available?

OROGO reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.

Need help selecting a product?

Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.

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