Modified Nucleosides
1,3-Dimethylpseudouridine
Quick view. A 1,3-dimethyl-substituted pseudouridine C-nucleoside identified by CAS 64272-68-0. CAS 64272-68-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
1,3-Dimethylpseudouridine is classified as modified nucleosides (Formula C11H16N2O6; molecular weight 272.25).
1,3-Dimethylpseudouridine — Reported as a C-nucleoside starting material in the published synthesis of 2'-deoxy C-nucleosides.
For 1,3-Dimethylpseudouridine, modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
Names and search terms
Useful catalog search terms
- 1,3-Dimethyl pseudouridine
- CAS 64272-68-0
Physicochemical data
| Systematic name | 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-dimethylpyrimidine-2,4-dione |
|---|---|
| Isomeric SMILES | CN1C=C(C(=O)N(C1=O)C)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
| InChIKey | UWLSSKRAONJGQX-BGZDPUMWSA-N |
| PubChem CID | 21854458 |
| InChI | InChI=1S/C11H16N2O6/c1-12-3-5(10(17)13(2)11(12)18)9-8(16)7(15)6(4-14)19-9/h3,6-9,14-16H,4H2,1-2H3/t6-,7-,8-,9+/m1/s1 |
| SMILES | CN1C=C(C(=O)N(C1=O)C)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
These points describe 1,3-Dimethylpseudouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.