Modified Nucleosides
2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine
Quick view. 2-Thiouridine derivative with both the 2'- and 3'-hydroxyl groups protected as TBDMS ethers. CAS 2305415-97-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine is classified as modified nucleosides (Formula C21H40N2O5SSi2; molecular weight 488.80 g/mol).
2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2',3'-Bis(O-tert-butyldimethylsilyl)-2-thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Bis-O-TBDMS-2-thiouridine
Useful catalog search terms
- 2305415-97-6
Physicochemical data
| PubChem CID | 168449893 |
|---|---|
| Nucleoside | 2-Thiouridine |
| Protecting groups | 2'-O-TBDMS; 3'-O-TBDMS |
| IUPAC name | 1-[(2R,3R,4R,5R)-3,4-bis[[tert-butyl(dimethyl)silyl]oxy]-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one |
| InChIKey | OTRKFKREBPGFCB-VDHUWJSZSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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