2'-FANA Nucleosides
2'-Deoxy-2'-fluoro-4-thio-beta-D-arabinouridine
Quick view. A beta-D-arabino 2'-fluoro nucleoside with a 4-thio pyrimidine base, identified as PubChem CID 168448675 and CAS 892145-76-5. CAS 892145-76-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-Deoxy-2'-fluoro-4-thio-beta-D-arabinouridine is classified as 2'-fana nucleosides (Formula C9H11FN2O4S; molecular weight 262.26).
2'-Deoxy-2'-fluoro-4-thio-beta-D-arabinouridine — 2'-FANA and thionucleoside building block for modified nucleoside research and further derivatization
For 2'-Deoxy-2'-fluoro-4-thio-beta-D-arabinouridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- CAS 892145-76-5
- PubChem CID 168448675
- C9H11FN2O4S
Physicochemical data
| PubChem CID | 168448675 |
|---|---|
| SMILES | C1=CN(C(=O)NC1=S)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F |
| Sugar configuration | 2'-Deoxy-2'-fluoro-beta-D-arabino |
| Thio position | Pyrimidine base C4 |
| Sugar-ring heteroatom | Oxygen retained |
| Free hydroxyl groups | 3' and 5' |
| InChIKey | LBXPACVSMLWUMQ-PXBUCIJWSA-N |
| InChI | InChI=1S/C9H11FN2O4S/c10-6-7(14)4(3-13)16-8(6)12-2-1-5(17)11-9(12)15/h1-2,4,6-8,13-14H,3H2,(H,11,15,17)/t4-,6+,7-,8-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoro-4-thio-beta-D-arabinouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.