2'-FANA Nucleosides
2'-Deoxy-2'-fluoroarabino inosine
Quick view. A 2'-fluoro-beta-D-arabinofuranosyl inosine derivative for FANA nucleoside chemistry. CAS 98983-40-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-Deoxy-2'-fluoroarabino inosine is classified as 2'-fana nucleosides (Formula C10H11FN4O4; molecular weight 270.22 g/mol).
2'-Deoxy-2'-fluoroarabino inosine — 2'-Fluoroarabino inosine building block for FANA nucleoside route development.
For 2'-Deoxy-2'-fluoroarabino inosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)hypoxanthine
Useful catalog search terms
- 2'-fluoroarabino inosine
- 98983-40-5
- C10H11FN4O4
- NRVOTDBYJXFINS-GQTRHBFLSA-N
Physicochemical data
| InChIKey | NRVOTDBYJXFINS-GQTRHBFLSA-N |
|---|---|
| Stereochemical form | 2'-Fluoro-beta-D-arabinofuranosyl inosine |
| PubChem CID | 135778987 |
| InChI | InChI=1S/C10H11FN4O4/c11-5-7(17)4(1-16)19-10(5)15-3-14-6-8(15)12-2-13-9(6)18/h2-5,7,10,16-17H,1H2,(H,12,13,18)/t4-,5+,7-,10-/m1/s1 |
| SMILES | C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoroarabino inosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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