Modified Nucleotides
3'-OMe-GMP TEA Salt
Quick view. The 1:1 triethylammonium salt of 3'-O-methylguanosine 5'-monophosphate, identified by CAS 860605-85-2 with a 3'-O-methyl group and 5'-monophosphate. CAS 860605-85-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-OMe-GMP TEA Salt is classified as modified nucleotides (Formula C17H31N6O8P; molecular weight 478.44).
3'-OMe-GMP TEA Salt can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For 3'-OMe-GMP TEA Salt, the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- 3'-O-methylguanosine 5'-monophosphate triethylammonium salt
- 5'-Guanylic acid, 3'-O-methyl-, compd. with N,N-diethylethanamine (1:1)
Useful catalog search terms
- CAS 860605-85-2
Physicochemical data
| Identity | 3'-O-methylguanosine 5'-monophosphate triethylammonium salt (1:1) |
|---|---|
| TEA composition | 1:1 |
| Modification pattern | 3'-O-methyl |
| Phosphate state | 5'-monophosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 3'-OMe-GMP TEA Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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