Modified Nucleosides
5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine
Quick view. A 5-hydroxymethyl-2-thiouridine derivative in which the 2' and 3' hydroxyl groups are protected as a single isopropylidene acetal. CAS 58479-71-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is classified as acetonide-protected 2-thiouridine derivative (Formula C13H18N2O6S; molecular weight 330.36 g/mol).
5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-O,3'-O-Isopropylidene-5-(hydroxymethyl)-2-thiouridine
Useful catalog search terms
- 58479-71-3
- MFCD25542462
Physicochemical data
| Protecting group | 2',3'-O-isopropylidene |
|---|---|
| MDL number | MFCD25542462 |
| PubChem CID | 53678259 |
| InChI | InChI=1S/C13H18N2O6S/c1-13(2)20-8-7(5-17)19-11(9(8)21-13)15-3-6(4-16)10(18)14-12(15)22/h3,7-9,11,16-17H,4-5H2,1-2H3,(H,14,18,22)/t7-,8-,9-,11-/m1/s1 |
| InChIKey | BETDENPMPLSMTA-TURQNECASA-N |
| SMILES | CC1(O[C@@H]2[C@H](O[C@H]([C@@H]2O1)N3C=C(C(=O)NC3=S)CO)CO)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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