Protected Nucleosides
5'-O-DMTr-Inosine
Quick view. A beta-D-ribofuranosyl inosine with selective 5'-O-(4,4'-dimethoxytrityl) protection, CAS 119898-59-8. CAS 119898-59-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-Inosine is classified as protected nucleosides (Formula C31H30N4O7; molecular weight 570.60).
A published route uses 5'-O-DMTr-inosine as an intermediate in preparing an inosine 3'-phosphoramidite for solid-phase oligonucleotide synthesis.
For 5'-O-DMTr-Inosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-rI
- 5'-O-(4,4'-dimethoxytrityl)-inosine
- 5'-O-DMT-inosine
Useful catalog search terms
- CAS 119898-59-8
- PubChem CID 135497173
Physicochemical data
| PubChem CID | 135497173 |
|---|---|
| InChIKey | PQXVLEMIGAJLIN-BQOYKFDPSA-N |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C5N=CNC6=O)O)O |
| Protecting group | 5'-O-(4,4'-dimethoxytrityl) |
| Ribose hydroxyl state | 2' and 3' hydroxyl groups unprotected |
| InChI | InChI=1S/C31H30N4O7/c1-39-22-12-8-20(9-13-22)31(19-6-4-3-5-7-19,21-10-14-23(40-2)15-11-21)41-16-24-26(36)27(37)30(42-24)35-18-34-25-28(35)32-17-33-29(25)38/h3-15,17-18,24,26-27,30,36-37H,16H2,1-2H3,(H,32,33,38)/t24-,26-,27-,30-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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