DMTr-protected Nucleosides
6'-O-DMTr-2',3'-dideoxy-Homo-C
Quick view. 6'-O-DMTr-2',3'-dideoxy-Homo-C is a DMTr-protected 2',3'-dideoxy homo-cytidine derivative identified by the manufacturer's exact product record. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
6'-O-DMTr-2',3'-dideoxy-Homo-C is classified as dmtr-protected nucleosides (Formula C31H33N3O5; molecular weight 527.60).
6'-O-DMTr-2',3'-dideoxy-Homo-C — DMTr-protected homo-cytidine intermediate for research route development.
For 6'-O-DMTr-2',3'-dideoxy-Homo-C, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 6'-O-DMT-2',3'-dideoxy-Homo-C
Physicochemical data
| CAS status | No public CAS Registry Number is listed for the reviewed product form. |
|---|---|
| Protecting-group pattern | 6'-O-DMTr |
| Sugar substitution | 2',3'-dideoxy homo-nucleoside |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 6'-O-DMTr-2',3'-dideoxy-Homo-C or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.