Halogenated Nucleosides
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine
Quick view. A beta-D purine nucleoside bearing a 3'-fluoro-3'-deoxy ribofuranosyl unit, CAS 124775-29-7. CAS 124775-29-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine is classified as halogenated nucleosides (Formula C10H11FN4O3; molecular weight 254.22).
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine — Primary literature reports this compound in a 3'-fluorinated purine nucleoside synthesis series.
For 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)purine
- 3'-Deoxy-3'-fluoropurine riboside
Useful catalog search terms
- CAS 124775-29-7
Physicochemical data
| SMILES | C1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O |
|---|---|
| Sugar configuration | beta-D-ribofuranosyl |
| Sugar modification | 3'-fluoro-3'-deoxy |
| PubChem CID | 77844500 |
| InChIKey | KIAXDTYQUWFQGP-FDDDBJFASA-N |
| InChI | InChI=1S/C10H11FN4O3/c11-7-6(2-16)18-10(8(7)17)15-4-14-5-1-12-3-13-9(5)15/h1,3-4,6-8,10,16-17H,2H2/t6-,7-,8-,10-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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