GalNAc
AdemA-GalNAc Phosphoramidite
Quick view. AdemA-GalNAc Phosphoramidite is a GalNAc-linked protected phosphoramidite identified by CAS 1953147-02-8 for nucleic acid synthesis. CAS 1953147-02-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
AdemA-GalNAc Phosphoramidite is classified as galnac (Formula C71H90N9O20P; molecular weight 1420.50).
AdemA-GalNAc Phosphoramidite — Phosphoramidite building block for nucleic acid synthesis.
For AdemA-GalNAc Phosphoramidite, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Useful catalog search terms
- CAS 1953147-02-8
- GalNAc
Physicochemical data
| InChIKey | BRDKHUNHNBOUJH-DVERYZRGSA-N |
|---|---|
| InChI | InChI=1S/C71H90N9O20P/c1-45(2)80(46(3)4)101(95-36-19-33-72)100-63-58(41-94-71(52-22-15-12-16-23-52,53-25-29-55(87-9)30-26-53)54-27-31-56(88-10)32-28-54)98-69(79-43-76-61-66(74-42-75-67(61)79)78-68(86)51-20-13-11-14-21-51)65(63)93-44-90-39-38-89-37-34-73-59(85)24-17-18-35-91-70-60(77-47(5)81)64(97-50(8)84)62(96-49(7)83)57(99-70)40-92-48(6)82/h11-16,20-23,25-32,42-43,45-46,57-58,60,62-65,69-70H,17-19,24,34-41,44H2,1-10H3,(H,73,85)(H,77,81)(H,74,75,78,86)/t57-,58-,60-,62+,63-,64-,65-,69-,70-,101?/m1/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OCOCCOCCNC(=O)CCCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C)N3C=NC4=C(N=CN=C43)NC(=O)C5=CC=CC=C5)COC(C6=CC=CC=C6)(C7=CC=C(C=C7)OC)C8=CC=C(C=C8)OC |
| Canonical SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OCOCCOCCNC(=O)CCCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C)N3C=NC4=C(N=CN=C43)NC(=O)C5=CC=CC=C5)COC(C6=CC=CC=C6)(C7=CC=C(C=C7)OC)C8=CC=C(C=C8)OC |
| PubChem CID | 156645982 |
| Structure representation | Exact protected AdemA-GalNAc phosphoramidite identity; phosphorus configuration is unspecified |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe AdemA-GalNAc Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
(6R)-FR054
GalNAc · CAS: 10378-06-0
OR-GALN-0003AdemC-GalNAc Phosphoramidite
GalNAc · CAS: N/A
OR-GALN-0004GalNAc PEG Cluster Phosphoramidite
GalNAc · CAS: N/A
OR-GALN-0005GalNAc-L96 Linker-Acid
GalNAc · CAS: 1426159-34-3
OR-GALN-0006GalNAc-L96 Linker-Azide
GalNAc · CAS: N/A
OR-GALN-0007Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
GalNAc · CAS: 175724-30-8
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.