2'-FANA Nucleosides
N4-Acetyl-2'-FANA-cytidine
Quick view. An N4-acetyl-protected cytidine derivative with a reviewed 2'-fluoro arabino configuration. CAS 2746366-21-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N4-Acetyl-2'-FANA-cytidine is classified as 2'-fana nucleosides (Formula C11H14FN3O5; molecular weight 287.24 g/mol).
N4-Acetyl-2'-FANA-cytidine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For N4-Acetyl-2'-FANA-cytidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 2746366-21-0
Physicochemical data
| PubChem CID | 124556178 |
|---|---|
| Systematic name | N-[1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide |
| Chemical form | Neutral N4-acetyl fluorinated cytidine derivative |
| Structural scope | N4-acetyl-protected cytidine with a 2'-fluoro arabino configuration |
| InChIKey | NLXVKEFNBVLDLD-XCWAXFADSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe N4-Acetyl-2'-FANA-cytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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