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OROGO PRODUCT CATEGORY

Linker Phosphoramidites

Quick view. Spacer, amino, thiol, phosphorylation and other linker phosphoramidites for oligonucleotide conjugation. This category currently includes 26 products. Linker Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

Products26
Use scopeResearch use only
Pack sizeCustomized to requirements
SupportSelection and custom synthesis review

Category guide

Typical use

Linker Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

How to select

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

How to qualify

Review identity, chromatographic purity, phosphorus-related quality attributes, water sensitivity and performance in a short test sequence.

Product-family considerations

Common advantages
  • Phosphoramidite chemistry is modular, automated and compatible with fast sequence iteration.
  • Modified sugar, base or linker motifs let researchers tune duplex stability, specificity, hydrophobicity, steric profile and downstream conjugation options.
Common limitations
  • Modified amidites can require adjusted coupling time, activator choice, deprotection conditions and analytical release methods.
  • Moisture sensitivity and storage history are important because degraded amidite can reduce coupling efficiency.

Category literature

These publications provide background for the Linker Phosphoramidites product family. Individual product pages only show additional product- or feature-relevant references.

Selection checklist

Exact identityMatch the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable.
SpecificationDefine target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits.
Workflow fitShare the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility.
Supply needProvide initial quantity, expected future scale, packaging preference, timeline and documentation requirements.

Product comparison

This snapshot compares up to eight products in the current catalog order. It uses published catalog fields only; confirm the exact form, pack size, specification and current availability by inquiry.

Swipe or scroll horizontally to compare all fields.

Product nameOR catalog no.CASPurity / specificationSupply statusChemical form
Thiol-Modifier C6 S-S CE PhosphoramiditeOR-LP-0016148254-21-1By inquiryInquiry onlyDMT-protected C6-disulfide-C6 2-cyanoethyl N,N-diisopropylphosphoramidite
2-O-DMTr-Sulfonyldiethanol-CE-PhosphoramiditeOR-LP-0010108783-02-4By inquiryInquiry onlyDMT-protected sulfonyldiethanol 2-cyanoethyl N,N-diisopropylphosphoramidite
5'-Amino-Modifier C6-TFA CE PhosphoramiditeOR-LP-0011133975-85-6By inquiryInquiry onlyN-TFA-protected C6 amino-linker 2-cyanoethyl N,N-diisopropylphosphoramidite
6-palmitamidohexyl CE PhosphoramiditeOR-LP-00121772522-18-5By inquiryInquiry onlyPalmitamido C6 2-cyanoethyl N,N-diisopropylphosphoramidite
Spacer C12 PhosphoramiditeOR-LP-0013158665-27-1By inquiryInquiry onlyDMT-protected C12 spacer 2-cyanoethyl N,N-diisopropylphosphoramidite
Spacer 9 PhosphoramiditeOR-LP-0025146668-73-7By inquiryInquiry onlyDMT-protected triethylene-glycol 2-cyanoethyl N,N-diisopropylphosphoramidite
Spacer 18 PhosphoramiditeOR-LP-0026125607-09-2By inquiryInquiry onlyDMT-protected hexaethylene-glycol 2-cyanoethyl N,N-diisopropylphosphoramidite
Chemical Phosphorylation Reagent IIOR-LP-0028171285-25-9By inquiryInquiry onlyDMT-protected diethyl-malonate 2-cyanoethyl N,N-diisopropylphosphoramidite

26 products

Chemical structure of Thiol-Modifier C6 S-S CE PhosphoramiditeThiol-Modifier C6 S-S CE Phosphoramidite

By inquiry · CAS: 148254-21-1

OR-LP-0016Chemical structure of 2-O-DMTr-Sulfonyldiethanol-CE-Phosphoramidite2-O-DMTr-Sulfonyldiethanol-CE-Phosphoramidite

By inquiry · CAS: 108783-02-4

OR-LP-0010Chemical structure of 5'-Amino-Modifier C6-TFA CE Phosphoramidite5'-Amino-Modifier C6-TFA CE Phosphoramidite

By inquiry · CAS: 133975-85-6

OR-LP-0011Chemical structure of 6-palmitamidohexyl CE Phosphoramidite6-palmitamidohexyl CE Phosphoramidite

By inquiry · CAS: 1772522-18-5

OR-LP-0012Chemical structure of Spacer C12 PhosphoramiditeSpacer C12 Phosphoramidite

By inquiry · CAS: 158665-27-1

OR-LP-0013Chemical structure of Spacer 9 PhosphoramiditeSpacer 9 Phosphoramidite

By inquiry · CAS: 146668-73-7

OR-LP-0025Chemical structure of Spacer 18 PhosphoramiditeSpacer 18 Phosphoramidite

By inquiry · CAS: 125607-09-2

OR-LP-0026Chemical structure of Chemical Phosphorylation Reagent IIChemical Phosphorylation Reagent II

By inquiry · CAS: 171285-25-9

OR-LP-0028Chemical structure of Solid Chemical Phosphorylation Reagent IISolid Chemical Phosphorylation Reagent II

By inquiry · CAS: 202284-84-2

OR-LP-0029Chemical structure of MMTr-C12 Amino-Linker PhosphoramiditeMMTr-C12 Amino-Linker Phosphoramidite

By inquiry · CAS: 178925-51-4

OR-LP-0031Chemical structure of MMTr-C6 Amino-Linker PhosphoramiditeMMTr-C6 Amino-Linker Phosphoramidite

By inquiry · CAS: 114616-27-2

OR-LP-0033Chemical structure of 5'-Hexynyl Phosphoramidite5'-Hexynyl Phosphoramidite

By inquiry · CAS: 1048985-37-0

OR-LP-0015Chemical structure of 5'-DBCO-TEG Phosphoramidite5'-DBCO-TEG Phosphoramidite

By inquiry · CAS: 1527468-08-1

OR-LP-0034Chemical structure of Spacer C3 PhosphoramiditeSpacer C3 Phosphoramidite

By inquiry · CAS: 110894-23-0

OR-LP-0023Chemical structure of Spacer C6 PhosphoramiditeSpacer C6 Phosphoramidite

By inquiry · CAS: 158041-82-8

OR-LP-0024Chemical structure of Cholesteryl-TEG PhosphoramiditeCholesteryl-TEG Phosphoramidite

By inquiry · CAS: 873435-29-1

OR-LP-0035Chemical structure of 5'-Cholesteryl-TEG Phosphoramidite5'-Cholesteryl-TEG Phosphoramidite

By inquiry · CAS: 1325147-19-0

OR-LP-0036Chemical structure of 5'-Maleimide-Modifier Phosphoramidite5'-Maleimide-Modifier Phosphoramidite

By inquiry · CAS: 1316303-83-9

OR-LP-0039Chemical structure of Spacer PEG-N3 PhosphoramiditeSpacer PEG-N3 Phosphoramidite

By inquiry · CAS: N/A

OR-LP-0014Chemical structure of standard-orientation dSpacer CE phosphoramiditeAbasic Phosphoramidite

By inquiry · CAS: 129821-76-7

OR-RP-0009Chemical structure of Spacer C2 PhosphoramiditeSpacer C2 Phosphoramidite

By inquiry · CAS: 161029-24-9

OR-LP-0022Chemical structure of Alpha-Tocopherol-TEG PhosphoramiditeAlpha-Tocopherol-TEG Phosphoramidite

By inquiry · CAS: 1621330-39-9

OR-LP-0037Chemical structure of 5'-Thiol-Modifier C65'-Thiol-Modifier C6

By inquiry · CAS: 116919-17-6

OR-LP-0038Chemical structure of DBCO-Serinol PhosphoramiditeDBCO-Serinol Phosphoramidite

By inquiry · CAS: N/A

OR-LP-0064Chemical structure of DBCO-dT-CE PhosphoramiditeDBCO-dT-CE Phosphoramidite

By inquiry · CAS: N/A

OR-LP-0065Chemical structure of Dithiol Serinol PhosphoramiditeDithiol Serinol Phosphoramidite

By inquiry · CAS: N/A

OR-LP-0069

Frequently asked questions

What are typical uses for Linker Phosphoramidites?

Linker Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

What should be confirmed before ordering Linker Phosphoramidites?

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

Are custom quantities or related analogs available?

OROGO reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.

Need help selecting a product?

Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.

Talk to a scientist Browse the complete catalog

General selection guidance for evaluating this product family. Confirm the exact product specification and workflow requirements separately.

How to evaluate phosphoramidites

Compare identity, protecting groups, modification, coupling, storage and deprotection fit.

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