Modified Nucleosides
2',3'-O-Isopropylidene-5-(pyrrolidin-1-ylmethyl)-2-thiouridine
Quick view. A protected C5 pyrrolidin-1-ylmethyl-substituted 2-thiouridine intermediate identified by CAS 89845-82-9. CAS 89845-82-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-O-Isopropylidene-5-(pyrrolidin-1-ylmethyl)-2-thiouridine is classified as modified nucleosides (Formula C17H25N3O5S; molecular weight 383.46).
2',3'-O-Isopropylidene-5-(pyrrolidin-1-ylmethyl)-2-thiouridine — Protected C5-substituted 2-thiouridine intermediate for further nucleoside chemistry
For 2',3'-O-Isopropylidene-5-(pyrrolidin-1-ylmethyl)-2-thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',3'-O-(1-Methylethylidene)-5-(1-pyrrolidinylmethyl)-2-thiouridine
- 2',3'-Di-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
Useful catalog search terms
- CAS 89845-82-9
- A328049
- IFJTVPASSJKUFD-RGCMKSIDSA-N
- PubChem CID 87560928
Physicochemical data
| Nucleoside | 2-Thiouridine |
|---|---|
| Ribose protection | 2',3'-O-isopropylidene |
| C5 substituent | Pyrrolidin-1-ylmethyl |
| Free hydroxyl | 5' hydroxymethyl |
| PubChem CID | 87560928 |
| InChIKey | IFJTVPASSJKUFD-RGCMKSIDSA-N |
| InChI | InChI=1S/C17H25N3O5S/c1-17(2)24-12-11(9-21)23-15(13(12)25-17)20-8-10(14(22)18-16(20)26)7-19-5-3-4-6-19/h8,11-13,15,21H,3-7,9H2,1-2H3,(H,18,22,26)/t11-,12-,13-,15-/m1/s1 |
| SMILES | CC1(O[C@@H]2[C@H](O[C@H]([C@@H]2O1)N3C=C(C(=O)NC3=S)CN4CCCC4)CO)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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