2'-FANA Nucleosides
2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine
Quick view. 2'-Fluoro-beta-D-arabino nucleoside bearing a 2-amino-N6,N6-dimethyladenine base. CAS 2171103-80-1. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine is classified as 2'-fana nucleosides (Formula C12H17FN6O3; molecular weight 312.31 g/mol).
2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- 2171103-80-1
Physicochemical data
| Nucleoside | 2-Amino-N6,N6-dimethyladenosine |
|---|---|
| Sugar configuration | 2'-deoxy-2'-fluoro-beta-D-arabino |
| InChIKey | KPARWUJDCIURDN-WCGPTHBMSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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