Amino-modified Nucleosides
2-Amino-N6,N6-dimethyl-2'-O-methyladenosine
Quick view. 2'-O-Methyl adenosine derivative bearing a 2-amino group and an N6,N6-dimethylamino substitution on the purine base. CAS 2095417-19-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2-Amino-N6,N6-dimethyl-2'-O-methyladenosine is classified as amino-modified nucleosides (Formula C13H20N6O4; molecular weight 324.34 g/mol).
2-Amino-N6,N6-dimethyl-2'-O-methyladenosine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 2-Amino-N6,N6-dimethyl-2'-O-methyladenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- 2095417-19-7
Physicochemical data
| Base modification | 2-amino-6-(dimethylamino)purine |
|---|---|
| Sugar modification | 2'-O-methyl |
| InChIKey | OXGQUZBFHLBMGI-WOUKDFQISA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2-Amino-N6,N6-dimethyl-2'-O-methyladenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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