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Halogenated Nucleosides

2'-Chloro-2'-deoxy-5-methyluridine

Quick view. A 5-methyluridine nucleoside with chlorine replacing the 2'-hydroxyl group on the sugar. CAS 54898-34-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.

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Chemical structure of 2'-Chloro-2'-deoxy-5-methyluridine
Chemical structure
Catalog numberOR-HN-0123
CAS number54898-34-9
PurityBy inquiry
Pack sizeCustom packaging by inquiry

Product profile

Material identity

2'-Chloro-2'-deoxy-5-methyluridine is classified as 2'-chloro 5-methyluridine nucleoside (Formula C10H13ClN2O5; molecular weight 276.67 g/mol).

Typical application

2'-Chloro-2'-deoxy-5-methyluridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.

Handling focus

For 2'-Chloro-2'-deoxy-5-methyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

PubChem CID101510
IUPAC name1-[(2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
InChIKeyWQMQACLYZYXSDZ-JXOAFFINSA-N
InChIInChI=1S/C10H13ClN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6-,7-,9-/m1/s1
SMILESCC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)Cl

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Product-family literature

These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.