2'-FANA Nucleosides
2'-Deoxy-2'-fluoro-beta-D-arabino-6-azauridine
Quick view. A 6-azauridine nucleoside bearing a 2'-deoxy-2'-fluoro-beta-D-arabino sugar modification. CAS 908129-24-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-Deoxy-2'-fluoro-beta-D-arabino-6-azauridine is classified as 2'-fana nucleosides (Formula C8H10FN3O5; molecular weight 247.18 g/mol).
2'-Deoxy-2'-fluoro-beta-D-arabino-6-azauridine — 2'-FANA nucleoside building block for downstream nucleoside chemistry.
For 2'-Deoxy-2'-fluoro-beta-D-arabino-6-azauridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 6-Aza-FANA uridine
- 908129-24-8
- C8H10FN3O5
Physicochemical data
| Sugar configuration | 2'-Deoxy-2'-fluoro-beta-D-arabino |
|---|---|
| Base feature | 6-Aza |
| PubChem CID | 91490554 |
| InChI | InChI=1S/C8H10FN3O5/c9-5-6(15)3(2-13)17-7(5)12-8(16)11-4(14)1-10-12/h1,3,5-7,13,15H,2H2,(H,11,14,16)/t3-,5+,6-,7-/m1/s1 |
| InChIKey | JVUOBMOHFKDKDS-VYNVVFCLSA-N |
| SMILES | O=c1cnn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F)c(=O)[nH]1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoro-beta-D-arabino-6-azauridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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