Succinates
N6-Bz-DMTr-2'-OMe-A-3'-succinate, TEA salt
Quick view. A protected N6-benzoyl 2'-O-methyladenosine 3'-succinate triethylamine salt for research-use oligonucleotide-synthesis workflows. CAS 2940857-85-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Identifier context
These notes preserve the current catalog identifiers while making their review boundary explicit.
The listed InChIKey and structure image represent the reviewed parent/free-acid moiety. The triethylammonium counterion is not depicted; confirm the exact supplied salt form with OROGO.
Product profile
N6-Bz-DMTr-2'-OMe-A-3'-succinate, TEA salt is classified as succinates.
N6-Bz-DMTr-2'-OMe-A-3'-succinate, TEA salt — Protected 2'-O-methyl adenosine succinate intermediate for research-use oligonucleotide-synthesis workflows.
For N6-Bz-DMTr-2'-OMe-A-3'-succinate, TEA salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-OMe-A(Bz) 3'-succinate, Triethylammonium salt
- DMT-2'-O-Me-A(Bz)-3'-succinate, TEA salt
- N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-O-succinate, triethylamine salt
- BRP-01226
Useful catalog search terms
- N6-Bz-DMTr-2'-OMe-A-3'-succinate TEA salt
- 2940857-85-0
- PubChem CID 168446487
- DMT-2'-O-Me-A(Bz)-3'-succinate
Physicochemical data
| CAS context | Parent/free-acid identity |
|---|---|
| Parent molecular formula | C43H41N5O10 |
| Parent molecular weight | 787.80 |
| TEA salt molecular formula | C49H56N6O10 |
| TEA salt molecular weight | 889.02 |
| PubChem CID | 168446487 |
| InChIKey | JGEUBEGMIVEEBB-FXTDJBBPSA-N |
| Nucleoside | N6-benzoyl 2'-O-methyladenosine |
| 3'-O group | Succinate |
| 5'-O group | DMTr |
| Salt form | Triethylamine salt |
| InChI | InChI=1S/C43H41N5O10/c1-53-31-18-14-29(15-19-31)43(28-12-8-5-9-13-28,30-16-20-32(54-2)21-17-30)56-24-33-37(58-35(51)23-22-34(49)50)38(55-3)42(57-33)48-26-46-36-39(44-25-45-40(36)48)47-41(52)27-10-6-4-7-11-27/h4-21,25-26,33,37-38,42H,22-24H2,1-3H3,(H,49,50)(H,44,45,47,52)/t33-,37-,38-,42-/m1/s1 |
| SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OC(=O)CCC(=O)O |
| Canonical SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OC(=O)CCC(=O)O |
| Structure representation | Parent/free-acid protected nucleoside-succinate moiety; triethylammonium counterion is not depicted |
| InChIKey review status | The listed InChIKey and structure image represent the reviewed parent/free-acid moiety. The triethylammonium counterion is not depicted; confirm the exact supplied salt form with OROGO. |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe N6-Bz-DMTr-2'-OMe-A-3'-succinate, TEA salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Succinates product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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