Modified Nucleosides
2-Thiothymidine
Quick view. A 2'-deoxythymidine derivative in which the base carries a 2-thioxo group. CAS 28585-51-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2-Thiothymidine is classified as modified nucleosides (Formula C10H14N2O4S; molecular weight 258.30 g/mol).
2-Thiothymidine is associated with thymidine-containing building blocks or substrates for DNA synthesis and analytical comparison.
For 2-Thiothymidine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2-Thio-2'-deoxythymidine
Useful catalog search terms
- 28585-51-5
Physicochemical data
| PubChem CID | 3005944 |
|---|---|
| Systematic name | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one |
| Structural scope | 2-thioxo thymine base with 2'-deoxyribose |
| InChIKey | PISWNSOQFZRVJK-XLPZGREQSA-N |
| InChI | InChI=1S/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1 |
| SMILES | Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=S)nc1O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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