Halogenated Nucleosides
3'-Deoxy-3'-fluoro-6-azauridine
Quick view. A 6-azauridine nucleoside bearing fluorine at sugar C3'. CAS 439579-23-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
3'-Deoxy-3'-fluoro-6-azauridine is classified as 3'-fluoro 6-aza uridine nucleoside (Formula C8H10FN3O5; molecular weight 247.18 g/mol).
3'-Deoxy-3'-fluoro-6-azauridine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 3'-Deoxy-3'-fluoro-6-azauridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 439579-23-4
- PRLLINGRDODXKC-SHUUEZRQSA-N
Physicochemical data
| PubChem CID | 69906586 |
|---|---|
| IUPAC name | 2-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione |
| InChIKey | PRLLINGRDODXKC-SHUUEZRQSA-N |
| InChI | InChI=1S/C8H10FN3O5/c9-5-3(2-13)17-7(6(5)15)12-8(16)11-4(14)1-10-12/h1,3,5-7,13,15H,2H2,(H,11,14,16)/t3-,5-,6-,7-/m1/s1 |
| SMILES | C1=NN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)F)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluoro-6-azauridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
Trifluridine
Halogenated Nucleosides · CAS: 70-00-8
OR-HN-00026-Chloropurine 2'-deoxyriboside
Halogenated Nucleosides · CAS: 4594-45-0
OR-HN-00038-Chloro-2'-deoxyadenosine
Halogenated Nucleosides · CAS: 85562-55-6
OR-HN-00042'-Chloro-2'-deoxycytidine
Halogenated Nucleosides · CAS: 10212-19-8
OR-HN-00055-Bromo-2'-deoxycytidine
Halogenated Nucleosides · CAS: 1022-79-3
OR-HN-01535-Fluoro-2'-deoxycytidine
Halogenated Nucleosides · CAS: 10356-76-0
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.