Modified Nucleosides
3-Methylpseudouridine
Quick view. A pseudouridine C-nucleoside bearing an N3-methyl modification, identified by CAS 81691-06-7. CAS 81691-06-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3-Methylpseudouridine is classified as modified nucleosides (Formula C10H14N2O6; molecular weight 258.23).
3-Methylpseudouridine is relevant to modified RNA, mRNA optimization, epitranscriptomic standards or immune-recognition studies depending on the format supplied.
For 3-Methylpseudouridine, modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
Names and search terms
Confirmed or normalized name variants
- 3-Methyl-5-beta-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
Useful catalog search terms
- CAS 81691-06-7
- PubChem CID 11207624
Physicochemical data
| PubChem CID | 11207624 |
|---|---|
| InChIKey | DXEJZRDJXRVUPN-XUTVFYLZSA-N |
| Nucleoside | pseudouridine C-nucleoside |
| Base modification | N3-methyl |
| Hydroxyl state | free 2', 3', and 5' hydroxyls |
| SMILES | CN1C(=O)C(=CNC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
| InChI | InChI=1S/C10H14N2O6/c1-12-9(16)4(2-11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,17)/t5-,6-,7-,8+/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
These points describe 3-Methylpseudouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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