Reverse Phosphoramidites
3'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-5'-CE-Phosphoramidite
Quick view. A no-public-CAS reverse-orientation 2'-O-MOE 5-methylcytidine phosphoramidite with formula C50H60N5O10P. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-5'-CE-Phosphoramidite is classified as reverse phosphoramidites (Formula C50H60N5O10P; molecular weight 922.03 g/mol).
3'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-5'-CE-Phosphoramidite is relevant to high-stability antisense oligonucleotide gapmer and affinity-tuning research.
For 3'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-5'-CE-Phosphoramidite, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Useful catalog search terms
- C50H60N5O10P
Physicochemical data
| CAS status | No public CAS assigned in the reviewed exact sources |
|---|---|
| Orientation | 3'-O-DMTr / 5'-CE reverse phosphoramidite |
| Protected form | N4-benzoyl 5-methylcytidine with 2'-O-MOE |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 3'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-5'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Reverse Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.
