Nucleoside Protection & Derivatization Reagents
4,4'-Dimethoxytriphenylmethyl chloride (DMT-Cl)
Quick view. A dimethoxytrityl reagent used for 5'-hydroxyl protection in nucleoside derivatization workflows. CAS 40615-36-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
4,4'-Dimethoxytriphenylmethyl chloride (DMT-Cl) is classified as nucleoside protection & derivatization reagents (Formula C21H19ClO2; molecular weight 338.80).
4,4'-Dimethoxytriphenylmethyl chloride (DMT-Cl) — 5'-Hydroxyl protection in nucleoside derivatization workflows.
For 4,4'-Dimethoxytriphenylmethyl chloride (DMT-Cl), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- DMT-Cl
- DMTr-Cl
- 4,4'-Dimethoxytrityl chloride
- Di-p-anisylphenylmethyl chloride
Useful catalog search terms
- 4,4'-Dimethoxytriphenylmethyl chloride
- CAS 40615-36-9
- PubChem CID 96831
Physicochemical data
| PubChem CID | 96831 |
|---|---|
| InChIKey | JBWYRBLDOOOJEU-UHFFFAOYSA-N |
| IUPAC name | 1-[chloro-(4-methoxyphenyl)-phenylmethyl]-4-methoxybenzene |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)Cl |
| Reagent class | Dimethoxytrityl hydroxyl-protecting reagent |
| InChI | InChI=1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.