Modified Nucleosides
4',5'-Didehydro-5'-deoxy-5-methyluridine
Quick view. An unsaturated 5-methyluridine derivative bearing a 4',5' exocyclic double bond and no 5'-hydroxyl, CAS 1446748-33-9. CAS 1446748-33-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
4',5'-Didehydro-5'-deoxy-5-methyluridine is classified as modified nucleosides (Formula C10H12N2O5; molecular weight 240.21).
4',5'-Didehydro-5'-deoxy-5-methyluridine — An unsaturated 5-methyluridine derivative for research use in modified pyrimidine nucleoside synthesis.
For 4',5'-Didehydro-5'-deoxy-5-methyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Uridine, 4',5'-didehydro-5'-deoxy-5-methyl-
- 1-(4,5-Dehydro-5-deoxy-beta-D-ribofuranosyl)thymine
- TNU1145
Useful catalog search terms
- 1446748-33-9
Physicochemical data
| Systematic identity synonym | 1-(4,5-Dehydro-5-deoxy-beta-D-ribofuranosyl)thymine |
|---|---|
| Nucleoside | 5-Methyluridine (thymine riboside) |
| Sugar unsaturation | 4',5' exocyclic double bond |
| Sugar modification | 5'-Deoxy |
| Hydroxyl state | Free 2' and 3' hydroxyls |
| PubChem CID | 67785162 |
| InChI | InChI=1S/C10H12N2O5/c1-4-3-12(10(16)11-8(4)15)9-7(14)6(13)5(2)17-9/h3,6-7,9,13-14H,2H2,1H3,(H,11,15,16)/t6-,7-,9-/m1/s1 |
| InChIKey | UZWBTYRRJMVEJY-ZXFLCMHBSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H](C(=C)O2)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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