Sugars
5-O-(p-Toluoyl)-1,2-di-O-acetyl-3-deoxy-3-fluoro-D-ribofuranose
Quick view. A protected, 3-deoxy-3-fluoro D-ribofuranose building block for structure-specific nucleoside synthesis research. CAS 1612192-28-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5-O-(p-Toluoyl)-1,2-di-O-acetyl-3-deoxy-3-fluoro-D-ribofuranose is classified as sugars (Formula C17H19FO7; molecular weight 354.30).
5-O-(p-Toluoyl)-1,2-di-O-acetyl-3-deoxy-3-fluoro-D-ribofuranose — Protected fluorinated ribofuranose building block for structure-specific nucleoside synthesis research.
For 5-O-(p-Toluoyl)-1,2-di-O-acetyl-3-deoxy-3-fluoro-D-ribofuranose, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 3'-F-Ribosugar
- 3-Deoxy-3-fluoro-D-ribofuranose 1,2-diacetate 5-(4-methylbenzoate)
Useful catalog search terms
- CAS 1612192-28-5
- protected fluorinated ribofuranose
- SYXLNQJSHVLYRK-BOEXNKMNSA-N
- PubChem CID 122397212
Physicochemical data
| Sugar modification | 3-deoxy-3-fluoro |
|---|---|
| Sugar protection | 1,2-di-O-acetyl; 5-O-(p-toluoyl) |
| Sugar configuration | D-ribofuranose; anomer not specified |
| PubChem CID | 122397212 |
| InChIKey | SYXLNQJSHVLYRK-BOEXNKMNSA-N |
| InChI | InChI=1S/C17H19FO7/c1-9-4-6-12(7-5-9)16(21)22-8-13-14(18)15(23-10(2)19)17(25-13)24-11(3)20/h4-7,13-15,17H,8H2,1-3H3/t13-,14-,15-,17?/m1/s1 |
| SMILES | CC(=O)OC1O[C@H](COC(=O)c2ccc(C)cc2)[C@@H](F)[C@H]1OC(C)=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5-O-(p-Toluoyl)-1,2-di-O-acetyl-3-deoxy-3-fluoro-D-ribofuranose or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Sugars product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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