dNTPs
7-Deaza-7-propargylamino-dGTP
Quick view. A propargylamino-modified deoxyguanosine triphosphate for gene-sequencing and nucleic-acid functionalization research. CAS 587848-73-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Identifier context
These notes preserve the current catalog identifiers while making their review boundary explicit.
This CAS number is shared by multiple OROGO catalog records. Confirm the exact salt, counterion, concentration and supplied form when requesting a quote.
Product profile
7-Deaza-7-propargylamino-dGTP is classified as dntps (Formula C14H20N5O13P3; molecular weight 559.26).
7-Deaza-7-propargylamino-dGTP — Modified-dGTP reagent for gene-sequencing research
For 7-Deaza-7-propargylamino-dGTP, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Useful catalog search terms
- 587848-73-5
Physicochemical data
| Nucleotide type | Modified deoxyguanosine triphosphate |
|---|---|
| Functional handle | Propargylamine |
| Storage temperature | -20 C for powder formats |
| PubChem CID | 162640848 |
| InChIKey | VJFQAGRGAURMEX-IVZWLZJFSA-N |
| InChI | InChI=1S/C14H20N5O13P3/c15-3-1-2-7-5-19(12-11(7)13(21)18-14(16)17-12)10-4-8(20)9(30-10)6-29-34(25,26)32-35(27,28)31-33(22,23)24/h5,8-10,20H,3-4,6,15H2,(H,25,26)(H,27,28)(H2,22,23,24)(H3,16,17,18,21)/t8-,9+,10+/m0/s1 |
| SMILES | NCC#Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c2nc(N)[nH]c(=O)c12 |
| CAS review status | This CAS number is shared by multiple OROGO catalog records. Confirm the exact salt, counterion, concentration and supplied form when requesting a quote. |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Propargylamine-handle functionalization before or after enzymatic DNA synthesis
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 7-Deaza-7-propargylamino-dGTP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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