Modified Nucleosides
2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine
Quick view. A protected uridine derivative bearing 2',3'-bis-TBDMS groups and a 4',5'-didehydro-5'-deoxy sugar unit, CAS 128070-78-0. CAS 128070-78-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine is classified as modified nucleosides (Formula C21H38N2O5Si2; molecular weight 454.71).
2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Bis-O-TBDMS-4',5'-didehydro-5'-deoxyuridine
- 2'-O,3'-O-bis(tert-butyldimethylsilyl)-4',5'-didehydro-5'-deoxyuridine
Useful catalog search terms
- CAS 128070-78-0
Physicochemical data
| Nucleobase | Uracil |
|---|---|
| Sugar modification | 4',5'-didehydro-5'-deoxy |
| Protecting groups | 2'-O-TBDMS; 3'-O-TBDMS |
| PubChem CID | 11259566 |
| InChI | InChI=1S/C21H38N2O5Si2/c1-14-16(27-29(8,9)20(2,3)4)17(28-30(10,11)21(5,6)7)18(26-14)23-13-12-15(24)22-19(23)25/h12-13,16-18H,1H2,2-11H3,(H,22,24,25)/t16-,17-,18-/m1/s1 |
| InChIKey | TYAQGUMZCVVFHL-KZNAEPCWSA-N |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](C(=C)O[C@H]1N2C=CC(=O)NC2=O)O[Si](C)(C)C(C)(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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