Modified Nucleosides
2',3'-Dideoxy-2',3'-didehydroinosine
Quick view. An unsaturated inosine analogue lacking the 2'- and 3'-hydroxyl groups and containing a C2'-C3' double bond, CAS 42867-68-5. CAS 42867-68-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-Dideoxy-2',3'-didehydroinosine is classified as unsaturated dideoxy purine nucleoside (Formula C10H10N4O3; molecular weight 234.21 g/mol).
2',3'-Dideoxy-2',3'-didehydroinosine — An unsaturated dideoxyinosine intermediate identified in a patent route to 2',3'-dideoxyinosine.
For 2',3'-Dideoxy-2',3'-didehydroinosine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Didehydro-2',3'-dideoxyinosine
- D4I
- 9-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)-1,9-dihydro-6H-purin-6-one
Useful catalog search terms
- 42867-68-5
- C10H10N4O3
- didehydro dideoxyinosine
- TYQPBHYPIRLWKU-NKWVEPMBSA-N
Physicochemical data
| InChIKey | TYQPBHYPIRLWKU-NKWVEPMBSA-N |
|---|---|
| Nucleobase | Hypoxanthine |
| Sugar modification | 2',3'-dideoxy with a C2'-C3' double bond |
| InChI | InChI=1S/C10H10N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h1-2,4-7,15H,3H2,(H,11,12,16)/t6-,7+/m0/s1 |
| SMILES | C1=C[C@@H](O[C@@H]1CO)N2C=NC3=C2NC=NC3=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- The exact compound is listed by NIFDC as an external reference standard for HPLC related-substance testing; OROGO grade and suitability require the current specification.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxy-2',3'-didehydroinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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