Modified Nucleosides
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxane-diyl)-2'-deoxyuridine
Quick view. A stereodefined 2'-deoxyuridine derivative bearing cyclic 3',5'-O-TIPDS protection, CAS 98495-56-8. CAS 98495-56-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxane-diyl)-2'-deoxyuridine is classified as modified nucleosides (Formula C21H38N2O6Si2; molecular weight 470.70 g/mol).
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxane-diyl)-2'-deoxyuridine — Cyclic 3',5'-O-TIPDS-protected 2'-deoxyuridine building block for modified nucleoside chemistry.
For 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxane-diyl)-2'-deoxyuridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine
- 3',5'-TIPS-2'-Deoxyuridine
- 3',5'-O-Tetraisopropyldisiloxanediyl-2'-deoxy-D-uridine
Useful catalog search terms
- 98495-56-8
- PubChem CID 13955091
- PEDMJTBGYAMVDO-NLWGTHIKSA-N
Physicochemical data
| PubChem CID | 13955091 |
|---|---|
| IUPAC name | 1-[(6aR,8R,9aS)-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]pyrimidine-2,4-dione |
| InChIKey | PEDMJTBGYAMVDO-NLWGTHIKSA-N |
| InChI | InChI=1S/C21H38N2O6Si2/c1-13(2)30(14(3)4)26-12-18-17(28-31(29-30,15(5)6)16(7)8)11-20(27-18)23-10-9-19(24)22-21(23)25/h9-10,13-18,20H,11-12H2,1-8H3,(H,22,24,25)/t17-,18+,20+/m0/s1 |
| SMILES | CC(C)[Si]1(OC[C@@H]2[C@H](C[C@@H](O2)N3C=CC(=O)NC3=O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
| Stereochemistry | (6aR,8R,9aS) protected sugar system |
| Protecting group | Cyclic 3',5'-O-TIPDS |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Reference compound for chemical identity research involving 3',5'-O-TIPDS-2'-deoxyuridine.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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