Halogenated Nucleosides
3'-Deoxy-3'-fluoro-N6-isopentenyl adenosine
Quick view. A halogenated adenosine derivative named for a 3'-deoxy-3'-fluoro modification and an N6-isopentenyl substituent. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-Deoxy-3'-fluoro-N6-isopentenyl adenosine is classified as halogenated nucleosides (Formula C15H20FN5O3; molecular weight 337.35 g/mol).
3'-Deoxy-3'-fluoro-N6-isopentenyl adenosine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 3'-Deoxy-3'-fluoro-N6-isopentenyl adenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Physicochemical data
| InChIKey | OXGRAAXMUFASNW-NDLNZWKESA-N |
|---|---|
| InChI | InChI=1S/C15H20FN5O3/c1-8(2)3-4-17-13-11-14(19-6-18-13)21(7-20-11)15-12(23)10(16)9(5-22)24-15/h3,6-7,9-10,12,15,22-23H,4-5H2,1-2H3,(H,17,18,19)/t9-,10-,12-,15-/m1/s1 |
| SMILES | CC(=CCNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)C |
| Canonical SMILES | CC(=CCNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)C |
| PubChem CID | 177700305 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluoro-N6-isopentenyl adenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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