Halogenated Nucleosides
3'-Deoxy-3'-fluorocytidine
Quick view. A cytidine nucleoside bearing fluorine at the 3' position of the ribofuranose unit, CAS 123402-20-0. CAS 123402-20-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-Deoxy-3'-fluorocytidine is classified as halogenated nucleosides (Formula C9H12FN3O4; molecular weight 245.21).
3'-Deoxy-3'-fluorocytidine — Primary literature places 3'-deoxy-3'-fluoro nucleosides in a documented nucleoside-synthesis research series.
For 3'-Deoxy-3'-fluorocytidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 3'-Fluoro-3'-deoxycytidine
- Cytidine, 3'-deoxy-3'-fluoro-
- 3'-F-3'-dC
- 4-amino-1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Useful catalog search terms
- CAS 123402-20-0
Physicochemical data
| InChI | InChI=1S/C9H12FN3O4/c10-6-4(3-14)17-8(7(6)15)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1 |
|---|---|
| InChIKey | PKOBNLOZXOHYOP-XVFCMESISA-N |
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)F)O |
| Nucleobase | Cytosine |
| Sugar modification | 3'-fluoro-3'-deoxy |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluorocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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