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Modified Nucleosides

3'-O-(tert-Butyldimethylsilyl)-2'-deoxyadenosine

Quick view. A 2'-deoxyadenosine derivative protected with a tert-butyldimethylsilyl group at O3'. CAS 51549-31-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.

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Chemical structure of 3'-O-(tert-Butyldimethylsilyl)-2'-deoxyadenosine
Chemical structure
Catalog numberOR-MN-0577
CAS number51549-31-6
PurityBy inquiry
Pack sizeCustom packaging by inquiry

Product profile

Material identity

3'-O-(tert-Butyldimethylsilyl)-2'-deoxyadenosine is classified as 3'-o-tbdms-2'-deoxyadenosine nucleoside (Formula C16H27N5O3Si; molecular weight 365.50 g/mol).

Typical application

3'-O-(tert-Butyldimethylsilyl)-2'-deoxyadenosine is associated with adenine-containing building blocks or substrates for A-position incorporation and analytical comparison.

Handling focus

For 3'-O-(tert-Butyldimethylsilyl)-2'-deoxyadenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Useful catalog search terms

Physicochemical data

PubChem CID10959475
IUPAC name[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-[tert-butyl(dimethyl)silyl]oxyoxolan-2-yl]methanol
InChIKeyRZJNKNBLADNWHG-QJPTWQEYSA-N
InChIInChI=1S/C16H27N5O3Si/c1-16(2,3)25(4,5)24-10-6-12(23-11(10)7-22)21-9-20-13-14(17)18-8-19-15(13)21/h8-12,22H,6-7H2,1-5H3,(H2,17,18,19)/t10-,11+,12+/m0/s1
SMILESCC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](O[C@@H]1CO)N2C=NC3=C(N=CN=C32)N

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Product-family literature

These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

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