DMTr-protected Nucleosides
5'-O-DMTr-2'-O-TBDMS-rC(Bz)
Quick view. N4-benzoyl-protected cytidine bearing a 5'-O-DMTr group, a 2'-O-TBDMS group and a free 3'-hydroxyl. CAS 81256-87-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-2'-O-TBDMS-rC(Bz) is classified as dmtr-protected nucleosides (Formula C43H49N3O8Si; molecular weight 763.95).
5'-O-DMTr-2'-O-TBDMS-rC(Bz) is supplied for research use within the DMTr-protected Nucleosides product family.
For 5'-O-DMTr-2'-O-TBDMS-rC(Bz), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N4-Benzoyl-5'-O-DMTr-2'-O-TBDMS-cytidine
- 5'-O-DMT-2'-O-TBDMS-N4-Bz-C
Useful catalog search terms
- CAS 81256-87-3
Physicochemical data
| Nucleoside | Cytidine |
|---|---|
| Base protection | N4-benzoyl |
| Hydroxyl protection | 5'-O-DMTr; 2'-O-TBDMS |
| Hydroxyl state | 3' hydroxyl group unprotected |
| InChI | InChI=1S/C43H49N3O8Si/c1-42(2,3)55(6,7)54-38-37(47)35(53-40(38)46-27-26-36(45-41(46)49)44-39(48)29-14-10-8-11-15-29)28-52-43(30-16-12-9-13-17-30,31-18-22-33(50-4)23-19-31)32-20-24-34(51-5)25-21-32/h8-27,35,37-38,40,47H,28H2,1-7H3,(H,44,45,48,49)/t35-,37-,38-,40-/m1/s1 |
| InChIKey | AOXWVTIMEGOVNF-PKGPUZNISA-N |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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