Modified Nucleosides
8-Methyl-2'-deoxyadenosine
Quick view. A 2'-deoxyadenosine derivative bearing an 8-methyl base modification, identified by CAS 85562-60-3. CAS 85562-60-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
8-Methyl-2'-deoxyadenosine is classified as modified nucleosides (Formula C11H15N5O3; molecular weight 265.27).
A retained 2005 Bioorganic & Medicinal Chemistry study reports incorporation of 8-methyl-2'-deoxyadenosine as A8Me in quadruplex-forming oligodeoxyribonucleotides (PMID 15670911; DOI 10.1016/j.bmc.2004.11.037).
For 8-Methyl-2'-deoxyadenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Useful catalog search terms
- CAS 85562-60-3
- PubChem CID 14132955
Physicochemical data
| PubChem CID | 14132955 |
|---|---|
| Nucleoside | 2'-deoxyadenosine |
| Base modification | 8-methyl |
| Free hydroxyls | 3'-OH and 5'-OH |
| InChI | InChI=1S/C11H15N5O3/c1-5-15-9-10(12)13-4-14-11(9)16(5)8-2-6(18)7(3-17)19-8/h4,6-8,17-18H,2-3H2,1H3,(H2,12,13,14)/t6-,7+,8+/m0/s1 |
| InChIKey | IJRWMSFJUAOOAR-XLPZGREQSA-N |
| SMILES | CC1=NC2=C(N=CN=C2N1[C@H]3C[C@@H]([C@H](O3)CO)O)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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