DNA Phosphoramidites
5'-O-DMTr-N2-isobutyryl-8-oxo-dG-3'-CE Phosphoramidite
Quick view. A 5'-O-DMTr and N2-isobutyryl-protected 8-oxo-dG 3'-CE phosphoramidite for research-use DNA oligonucleotide synthesis, identified by CAS 143060-53-1. CAS 143060-53-1. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-N2-isobutyryl-8-oxo-dG-3'-CE Phosphoramidite is classified as dna phosphoramidites (Formula C44H54N7O9P; molecular weight 855.91).
5'-O-DMTr-N2-isobutyryl-8-oxo-dG-3'-CE Phosphoramidite — A CE phosphoramidite building block for research-use DNA oligonucleotide synthesis.
For 5'-O-DMTr-N2-isobutyryl-8-oxo-dG-3'-CE Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 8-OXO-N2-isobutyryl-deoxyguanosine-5'-cyanoethyl Phosphoramidite
- 8-Oxo-dG CE-Phosphoramidite
- 2-Deoxy-5'-O-DMT-N2-isobutyryl-8-oxoguanosine 3'-CE phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
Useful catalog search terms
- CAS 143060-53-1
- PubChem CID 136799210
Physicochemical data
| PubChem CID | 136799210 |
|---|---|
| InChIKey | YLGHZAYWNYAERE-MXWPLEIRSA-N |
| Nucleoside | 8-oxo-2'-deoxyguanosine |
| Base protection | N2 isobutyryl |
| 5' protection | DMTr |
| 3' functionality | 2-cyanoethyl N,N-diisopropylphosphoramidite |
| Phosphorus stereochemistry | unspecified |
| InChI | InChI=1S/C44H54N7O9P/c1-27(2)40(52)48-42-47-39-38(41(53)49-42)46-43(54)50(39)37-25-35(60-61(58-24-12-23-45)51(28(3)4)29(5)6)36(59-37)26-57-44(30-13-10-9-11-14-30,31-15-19-33(55-7)20-16-31)32-17-21-34(56-8)22-18-32/h9-11,13-22,27-29,35-37H,12,24-26H2,1-8H3,(H,46,54)(H2,47,48,49,52,53)/t35-,36+,37+,61?/m0/s1 |
| SMILES | CC(C)C(=O)NC1=NC2=C(C(=O)N1)NC(=O)N2[C@H]3C[C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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