2'-O-Me Phosphoramidites
5'-O-DMTr-2'-O-Me-uridine-3'-(L)-PSM phosphoramidite
Quick view. A stereodefined L-PSM phosphoramidite of 5'-O-DMTr-protected 2'-O-methyluridine for oligonucleotide synthesis research. CAS 2963598-67-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-2'-O-Me-uridine-3'-(L)-PSM phosphoramidite is classified as 2'-o-me phosphoramidites (Formula C43H46N3O11PS; molecular weight 843.88).
5'-O-DMTr-2'-O-Me-uridine-3'-(L)-PSM phosphoramidite — Protected stereodefined L-PSM uridine phosphoramidite monomer for oligonucleotide synthesis research.
For 5'-O-DMTr-2'-O-Me-uridine-3'-(L)-PSM phosphoramidite, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- DMTr-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite
Useful catalog search terms
- CAS 2963598-67-4
- WALZCFCZIWHBMO-NRIQKVBLSA-N
Physicochemical data
| InChIKey | WALZCFCZIWHBMO-NRIQKVBLSA-N |
|---|---|
| Nucleoside | 5'-O-DMTr-2'-O-methyluridine |
| Chiral auxiliary | (L)-PSM cyclic phosphoramidite |
| Stereochemical boundary | Reagent stereochemistry defined; final linkage outcome not asserted |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5'-O-DMTr-2'-O-Me-uridine-3'-(L)-PSM phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.