RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite
Quick view. DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite is an N6-methyladenosine and 2'-O-TBDMS protected building block for research-use RNA oligonucleotide synthesis. CAS 588698-79-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite is classified as modified riboadenosine phosphoramidite (Formula C47H64N7O7PSi; molecular weight 898.10).
DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite — N6-methyladenosine and 2'-O-TBDMS protected phosphoramidite building block for research-use RNA oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N6-Me-rA Phosphoramidite
- N6-Methyl-rA Phosphoramidite
- DMT-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite
Useful catalog search terms
- 588698-79-7
- PubChem 12994120
- C47H64N7O7PSi
- Areterna PA026
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Nucleoside modification | N6-methyladenosine |
|---|---|
| Ribose protection | 2'-O-TBDMS |
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | GPLFLRPEMRRWIR-UTZPQXNGSA-N |
| InChI | InChI=1S/C47H64N7O7PSi/c1-32(2)54(33(3)4)62(58-28-16-27-48)60-41-39(59-45(42(41)61-63(11,12)46(5,6)7)53-31-52-40-43(49-8)50-30-51-44(40)53)29-57-47(34-17-14-13-15-18-34,35-19-23-37(55-9)24-20-35)36-21-25-38(56-10)26-22-36/h13-15,17-26,30-33,39,41-42,45H,16,28-29H2,1-12H3,(H,49,50,51)/t39-,41-,42-,45-,62?/m1/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC |
| PubChem CID | 12994120 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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