RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite
Quick view. DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite is an N4-acetyl- and 2'-O-TBDMS-protected cytidine building block for research-use RNA oligonucleotide synthesis. CAS 121058-88-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite is classified as protected ribocytidine phosphoramidite (Formula C47H64N5O9PSi; molecular weight 902.10).
DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite — N4-acetyl- and 2'-O-TBDMS-protected cytidine phosphoramidite building block for research-use RNA oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Ac-rC Phosphoramidite
- DMT-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite
- 2'-O-TBDMS-rC(Ac) Phosphoramidite
Useful catalog search terms
- 121058-88-6
- C47H64N5O9PSi
- Areterna PA010
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Base protection | N4-acetyl |
|---|---|
| Ribose protection | 2'-O-TBDMS |
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChI | InChI=1S/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(58-30-16-28-48)60-42-40(59-44(43(42)61-63(11,12)46(6,7)8)51-29-27-41(49-34(5)53)50-45(51)54)31-57-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/m0/s1 |
| InChIKey | QKWKXYVKGFKODW-ZYRNLWDWSA-N |
| SMILES | COc1ccc(C(OC[C@@H]2O[C@H](n3ccc(NC(C)=O)nc3=O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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