RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rC(Bz)-3'-CE-Phosphoramidite
Quick view. DMTr-2'-O-TBDMS-rC(Bz)-3'-CE-Phosphoramidite is an N4-benzoyl- and 2'-O-TBDMS-protected cytidine building block for research-use RNA oligonucleotide synthesis. CAS 118380-84-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
DMTr-2'-O-TBDMS-rC(Bz)-3'-CE-Phosphoramidite is classified as protected ribocytidine phosphoramidite (Formula C52H66N5O9PSi; molecular weight 964.20).
DMTr-2'-O-TBDMS-rC(Bz)-3'-CE-Phosphoramidite — N4-benzoyl- and 2'-O-TBDMS-protected cytidine phosphoramidite building block for research-use RNA oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-rC(Bz)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Bz-rC Phosphoramidite
- DMT-2'-O-TBDMS-rC(Bz)-3'-CE-Phosphoramidite
- N4-Benzoyl-2'-O-TBDMS-5'-O-DMT-cytidine-3'-CE phosphoramidite
Useful catalog search terms
- 118380-84-0
- PubChem 11029435
- C52H66N5O9PSi
- Areterna PA036
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Base protection | N4-benzoyl |
|---|---|
| Ribose protection | 2'-O-TBDMS |
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | VWNXEDLLHIFAOL-YOVDOAOFSA-N |
| InChI | InChI=1S/C52H66N5O9PSi/c1-36(2)57(37(3)4)67(63-34-18-32-53)65-46-44(35-62-52(39-21-16-13-17-22-39,40-23-27-42(60-8)28-24-40)41-25-29-43(61-9)30-26-41)64-49(47(46)66-68(10,11)51(5,6)7)56-33-31-45(55-50(56)59)54-48(58)38-19-14-12-15-20-38/h12-17,19-31,33,36-37,44,46-47,49H,18,34-35H2,1-11H3,(H,54,55,58,59)/t44-,46-,47-,49-,67?/m1/s1 |
| SMILES | COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=NC(=O)c4ccccc4)nc3O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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