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Phosphorus Reagents

N,N,N',N'-Tetramethylphosphorodiamidic chloride

Quick view. A bis(dimethylamino) phosphoryl chloride reagent for preparation of amino-substituted phosphorus intermediates. CAS 1605-65-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.

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Chemical structure of N,N,N',N'-Tetramethylphosphorodiamidic chloride
Chemical structure
Catalog numberOR-PR-0012
CAS number1605-65-8
PurityBy inquiry
Pack size5 g and 25 g; custom packaging by inquiry

Product profile

Material identity

N,N,N',N'-Tetramethylphosphorodiamidic chloride is classified as phosphorus reagents (Formula C4H12ClN2OP; molecular weight 170.58).

Typical application

N,N,N',N'-Tetramethylphosphorodiamidic chloride — Phosphorylating reagent for preparation of amino-substituted phosphorus intermediates

Handling focus

For N,N,N',N'-Tetramethylphosphorodiamidic chloride, storage: Cool and dark below 15 C; store under inert gas and protect from moisture. Form: Colorless to light-yellow/light-orange clear liquid.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

IUPAC nameN-[chloro(dimethylamino)phosphoryl]-N-methylmethanamine
InChIKeyWYLQARGYFXBZMD-UHFFFAOYSA-N
SMILESCN(C)P(=O)(N(C)C)Cl
FormColorless to light-yellow/light-orange clear liquid
Density1.152 g/mL at 25 C
Boiling Point110 C at 11 mmHg
Refractive Index1.466-1.47
PubChem CID74150
InChIInChI=1S/C4H12ClN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Additional application examples

Related products

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