Other Protected Nucleosides
2',3'-di-O-iBu-rG(iBu)
Quick view. 2',3'-di-O-iBu-rG(iBu) is guanosine protected with an N2-isobutyryl group and 2'-O- and 3'-O-isobutyryl esters, while the 5'-hydroxyl remains unprotected. CAS 56489-75-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-di-O-iBu-rG(iBu) is classified as other protected nucleosides (Formula C22H31N5O8; molecular weight 493.50).
2',3'-di-O-iBu-rG(iBu) — Protected guanosine intermediate for research route development where the 5'-hydroxyl remains available for subsequent transformation.
For 2',3'-di-O-iBu-rG(iBu), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N2-isobutyryl-2',3'-di-O-isobutyrylguanosine
- Guanosine, N-(2-methyl-1-oxopropyl)-, 2',3'-bis(2-methylpropanoate)
Useful catalog search terms
- CAS 56489-75-9
Physicochemical data
| Protecting-group pattern | N2-isobutyryl; 2'-O-isobutyryl; 3'-O-isobutyryl |
|---|---|
| Unprotected position | 5'-hydroxyl |
| Ribose stereochemistry | (2R,3R,4R,5R) |
| Systematic name | [(2R,3R,4R,5R)-2-(hydroxymethyl)-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]-4-(2-methylpropanoyloxy)oxolan-3-yl] 2-methylpropanoate |
| InChIKey | JJRMTPVXETZPOA-QEPJRFBGSA-N |
| PubChem CID | 140862743 |
| InChI | InChI=1S/C22H31N5O8/c1-9(2)17(29)25-22-24-16-13(18(30)26-22)23-8-27(16)19-15(35-21(32)11(5)6)14(12(7-28)33-19)34-20(31)10(3)4/h8-12,14-15,19,28H,7H2,1-6H3,(H2,24,25,26,29,30)/t12-,14-,15-,19-/m1/s1 |
| SMILES | CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)OC(=O)C(C)C)OC(=O)C(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Product-family literature
These publications provide peer-reviewed context for the Other Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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