Modified Nucleosides
2',3'-Dideoxyinosine
Quick view. A modified inosine nucleoside lacking the 2' and 3' hydroxyl groups, identified by CAS 69655-05-6. CAS 69655-05-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-Dideoxyinosine is classified as modified nucleosides (Formula C10H12N4O3; molecular weight 236.23).
2',3'-Dideoxyinosine can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For 2',3'-Dideoxyinosine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- Didanosine
Useful catalog search terms
- CAS 69655-05-6
- PubChem CID 135398739
Physicochemical data
| Nucleobase | Hypoxanthine |
|---|---|
| Sugar modification | 2',3'-Dideoxy |
| Available hydroxyl | 5'-OH |
| InChIKey | BXZVVICBKDXVGW-NKWVEPMBSA-N |
| PubChem CID | 135398739 |
| InChI | InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1 |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=NC3=C2NC=NC3=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxyinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.