Ara Nucleosides
2'-Amino-2'-deoxy-beta-D-arabino-5-methyluridine
Quick view. A beta-D-arabino 5-methyluridine bearing a 2'-amino-2'-deoxy sugar modification, CAS 135304-48-2. CAS 135304-48-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-Amino-2'-deoxy-beta-D-arabino-5-methyluridine is classified as ara nucleosides (Formula C10H15N3O5; molecular weight 257.24).
2'-Amino-2'-deoxy-beta-D-arabino-5-methyluridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 2'-Amino-2'-deoxy-beta-D-arabino-5-methyluridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 5-Methyl-2'-amino-2'-deoxy-beta-D-arabinouridine
- 2'-Amino-2'-deoxy-5-methyl-beta-D-arabinouridine
- 2'-NH2-ara-5-MeU
Useful catalog search terms
- CAS 135304-48-2
Physicochemical data
| Sugar configuration | beta-D-Arabino |
|---|---|
| Sugar substitution | 2'-amino-2'-deoxy |
| Nucleobase | 5-Methyluracil |
| PubChem CID | 15277239 |
| InChI | InChI=1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h2,5-7,9,14-15H,3,11H2,1H3,(H,12,16,17)/t5-,6+,7-,9-/m1/s1 |
| InChIKey | VGYZEXPNNAEQKL-JVZYCSMKSA-N |
| SMILES | Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2N)c(=O)[nH]c1=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-Amino-2'-deoxy-beta-D-arabino-5-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Ara Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.