Amino-modified Nucleosides
2-Amino-2',3'-dideoxyadenosine
Quick view. 2-Amino-2',3'-dideoxyadenosine is a 2,6-diaminopurine dideoxyriboside with CAS 107550-73-2. CAS 107550-73-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2-Amino-2',3'-dideoxyadenosine is classified as amino-modified dideoxynucleoside (Formula C10H14N6O2; molecular weight 250.26 (calculated from molecular formula)).
2-Amino-2',3'-dideoxyadenosine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 2-Amino-2',3'-dideoxyadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2,6-Diaminopurine 2',3'-dideoxyriboside
Useful catalog search terms
- CAS 107550-73-2
- Amino-modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H14N6O2/c11-8-7-9(15-10(12)14-8)16(4-13-7)6-2-1-5(3-17)18-6/h4-6,17H,1-3H2,(H4,11,12,14,15)/t5-,6+/m0/s1 |
|---|---|
| InChIKey | OABUIHOVHQHUAO-NTSWFWBYSA-N |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=NC3=C(N=C(N=C32)N)N |
| Structural features | 2,6-Diaminopurine linked to a 2',3'-dideoxyriboside |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2-Amino-2',3'-dideoxyadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.