2'-FANA Nucleosides
2'-FANA-dG
Quick view. 2'-FANA-dG is a 2'-fluoro-arabino guanosine building block for research-use modified-nucleoside and oligonucleotide chemistry. CAS 103884-98-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-FANA-dG is classified as 2'-fluoro-arabino nucleoside (Formula C10H12FN5O4; molecular weight 285.23).
2'-FANA-dG — A 2'-fluoro-arabino guanosine building block for research-use modified-nucleoside and oligonucleotide chemistry.
For 2'-FANA-dG, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2'-FANA-G
- 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine
- 9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine
- 2'-deoxy-2'-fluoro-arabino-guanosine
Useful catalog search terms
- CAS 103884-98-6
- OR-2FAN-0037
- OR-2FAN-0042
Physicochemical data
| PubChem CID | 135625251 |
|---|---|
| InChIKey | UXUZARPLRQRNNX-VPRFCXCPSA-N |
| Modification | 2'-Deoxy-2'-fluoro-arabino guanosine |
| InChI | InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4+,6-,9?/m1/s1 |
| SMILES | N=c1nc(O)c2ncn(C3O[C@H](CO)[C@@H](O)[C@@H]3F)c2[nH]1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-FANA-dG or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.