TIPDS-protected Nucleosides
3',5'-O-TIPDS-rC(Ac)
Quick view. 3',5'-O-TIPDS-rC(Ac) is N4-acetylcytidine protected by a 3',5'-O-TIPDS bridge, leaving the 2'-hydroxyl unprotected. CAS 85335-73-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3',5'-O-TIPDS-rC(Ac) is classified as tipds-protected nucleosides (Formula C23H41N3O7Si2; molecular weight 527.80).
3',5'-O-TIPDS-rC(Ac) — Protected cytidine intermediate for research route development involving the free 2'-hydroxyl.
For 3',5'-O-TIPDS-rC(Ac), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N4-acetyl-3',5'-O-TIPDS-cytidine
Useful catalog search terms
- CAS 85335-73-5
Physicochemical data
| Protecting-group pattern | N4-acetyl; 3',5'-O-TIPDS bridge |
|---|---|
| Unprotected position | 2'-hydroxyl |
| Encoded stereochemistry | (6aR,8R,9R,9aS) |
| Systematic name | N-[1-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide |
| InChIKey | DQGHXFWTOQROJQ-ZHHKINOHSA-N |
| InChI | InChI=1S/C23H41N3O7Si2/c1-13(2)34(14(3)4)30-12-18-21(32-35(33-34,15(5)6)16(7)8)20(28)22(31-18)26-11-10-19(24-17(9)27)25-23(26)29/h10-11,13-16,18,20-22,28H,12H2,1-9H3,(H,24,25,27,29)/t18-,20-,21-,22-/m1/s1 |
| SMILES | CC(C)[Si]1(OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=NC3=O)NC(=O)C)O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
| Canonical SMILES | CC(C)[Si]1(OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=NC3=O)NC(=O)C)O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the TIPDS-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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