Halogenated Nucleosides
3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine
Quick view. A xylo-configured 5-methyluridine derivative bearing a 3'-deoxy-3'-fluoro sugar modification. CAS 917110-29-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine is classified as halogenated nucleosides (Formula C10H13FN2O5; molecular weight 260.22 g/mol).
3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine — Halogenated xylo-uridine building block for downstream nucleoside chemistry.
For 3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 3'-Deoxy-3'-fluoro-5-methylxylouridine
- 917110-29-3
- C10H13FN2O5
Physicochemical data
| Nucleoside | 5-Methyluridine derivative |
|---|---|
| Sugar configuration | xylo |
| Sugar modification | 3'-Deoxy-3'-fluoro |
| PubChem CID | 11608602 |
| InChI | InChI=1S/C10H13FN2O5/c1-4-2-13(10(17)12-8(4)16)9-7(15)6(11)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6+,7-,9-/m1/s1 |
| InChIKey | XFLCLDYCKOUGAR-JVZYCSMKSA-N |
| SMILES | Cc1cn([C@@H]2O[C@H](CO)[C@H](F)[C@H]2O)c(=O)[nH]c1=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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