Base-protected Nucleosides
3'-O-Me-rA(Bz)
Quick view. N6-Benzoyladenosine bearing a 3'-O-methyl group with free 2'- and 5'-hydroxyl groups. CAS 85090-30-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-O-Me-rA(Bz) is classified as base-protected nucleosides (Formula C18H19N5O5; molecular weight 385.37).
3'-O-Me-rA(Bz) can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For 3'-O-Me-rA(Bz), the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- N6-Benzoyl-3'-O-methyladenosine
- N6-Benzoyl-3'-O-methyl-D-adenosine
Useful catalog search terms
- CAS 85090-30-8
Physicochemical data
| Nucleoside | N6-Benzoyladenosine |
|---|---|
| Sugar modification | 3'-O-methyl |
| Hydroxyl state | 2' and 5' hydroxyl groups unprotected |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 3'-O-Me-rA(Bz) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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