Protected Nucleosides
3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
Quick view. An orthogonally protected 2'-deoxyadenosine bearing 3'-O-TBDMS and 5'-O-DMTr groups, identified by CAS 89947-86-4. CAS 89947-86-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is classified as protected nucleosides (Formula C37H45N5O5Si; molecular weight 667.87).
3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine — Orthogonally protected 2'-deoxyadenosine intermediate for further nucleoside and oligonucleotide building-block chemistry
For 3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine
- 3'-O-tert-Butyldimethylsilyl-2'-deoxy-5'-O-DMT-adenosine
Useful catalog search terms
- 3'-O-TBDMS-5'-O-DMTr-2'-deoxyadenosine
- CAS 89947-86-4
- CB33334257
Physicochemical data
| Nucleoside | beta-D-2'-Deoxyadenosine |
|---|---|
| 3' protection | O-TBDMS |
| 5' protection | O-DMTr |
| Adenine N6 | Unprotected amino group |
| Free ribose hydroxyls | None |
| PubChem CID | 11093601 |
| InChI | InChI=1S/C37H45N5O5Si/c1-36(2,3)48(6,7)47-30-21-32(42-24-41-33-34(38)39-23-40-35(33)42)46-31(30)22-45-37(25-11-9-8-10-12-25,26-13-17-28(43-4)18-14-26)27-15-19-29(44-5)20-16-27/h8-20,23-24,30-32H,21-22H2,1-7H3,(H2,38,39,40)/t30-,31+,32+/m0/s1 |
| InChIKey | BLILIIKIHHYPLG-DCMFLLSESA-N |
| SMILES | CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C(N=CN=C65)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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